Dietary Supplement Adulteration: Laboratory Approaches to Risk Mitigation.

Adulteration issues are a continuous problem facing dietary supplements (DS) manufacturers. In the past few years, major supply chain disruptions have further led to increased risk of adulteration. DS manufacturers selling products in the U.S. are required to comply with GMP, which include quality control testing to ensure that the products meet specifications for identity, purity, strength and composition, and limits on contaminants. In addition to quality control testing with compendial methods, tools to help the DS industry mitigate risks associated with adulteration include DS certification or verification programs, quality agreements with suppliers, and third-party testing.