Pediatric Constipation: What Can We Learn from the Adult Gastroenterologist?

Ilan J N Koppen, Daniel Keszthelyi, Marc A Benninga, Michelle N Bloem

Journal: Gastroenterology clinics of North America 2025;54(3):597-613

PMID: 40752919

Full Text on Elsevier Science View on PubMed

Abstract

Functional constipation is a common pediatric problem with significant impact on quality of life. Effective management requires a combination of behavioral strategies and pharmacologic treatments. This article discusses current pediatric approaches, evaluates how insights from adult gastroenterology can be implemented in pediatric care, and explores emerging therapies with the potential for pediatric use. Additionally, it addresses challenges in pediatric constipation management and the future research directions.

Address: Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Amsterdam University Medical Center (UMC), University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism Research Institute, Amsterdam UMC, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands. Electronic address: [email protected].; Department of Gastroenterology-Hepatology, Maastricht University Medical Center+, Maastricht University, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands.; Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Amsterdam University Medical Center (UMC), University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands.

DOI: 10.1016/j.gtc.2025.01.002

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MeSH Terms: Humans, Constipation, Child, Gastroenterology, Adult, Laxatives, Gastroenterologists