Hypertensive crisis occurs as a new aftermath beyond post-heatstroke: A case report and literature review.

Lei Li, Junda Cao, Fangqi Zhang

Journal: Medicine 2025;104(31):e43761

PMID: 40760521

Abstract

RATIONALE

Heatstroke is a life-threatening condition and the most severe form of heat-related illness, characterized by a body temperature exceeding 40°C and multiorgan failure. In the cardiovascular system, hypovolemic shock is common. There is no report of hypertensive emergencies occurring during recovery from heatstroke.

PATIENT CONCERNS

This case study presents a 55-year-old male who was initially admitted with a lung abscess, which continued to improve during hospitalization, but he subsequently developed heatstroke due to outdoor activities in high-temperature environments. During recovery from multiple organ dysfunction caused by heatstroke, the patient experienced a month-long hypertensive emergency.

DIAGNOSES

After ruling out hypertension caused by infection, the persistent hypertension in the patient was highly suspected to be caused by heatstroke.

INTERVENTIONS

The patient was transferred to an air-conditioned room, and symptomatic supportive treatment for heatstroke was initiated. Sodium nitroprusside was administered intravenously to treat the hypertensive crisis, while Nifedipine, Metoprolol, and Irbesartan were given orally for subsequent hypertension. Finally, the patient's blood pressure gradually stabilized and remained so until the medications were discontinued.

OUTCOMES

His symptoms basically disappeared within 1 month, and the patient did not report any discomfort with 8 months of follow-up.

LESSONS

This case was the first report of hypertensive emergencies during recovery from heatstroke. The possible mechanisms of hypertensive emergencies during recovery from heatstroke had been explored in this case study though literature review.

Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc.

Address: Department of Thoracic Surgery, Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.; Hubei Clinical Research Center Diseases, Wuhan, China.; Wuhan Research for Infectious Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, Wuhan, China.; Jiujiang City Key Laboratory of Cell Therapy, Department of Cardiovascular, The First Hospital of Jiujiang City, Jiujiang, China.; Department of Pulmonary and Critical Care Medicine, The 987th Hospital of Joint Logistics Support Force of People's Liberation Army, Baoji, China.
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