Robyn Tapp, Rebecca L Thomas, David R Owens, Dimitrios Kazantzis, Sarega Gurudas, Sobha Sivaprasad, Farhan Zaidi, Lizzy Evans
Journal: Diabetes research and clinical practice 2025;226():112346
PMID: 40578519
AIMS
This study aimed to report the global prevalence of diabetic retinopathy (DR) based on retinal imaging, using English-language articles published from 2017 to June 2024.
METHODS
Three databases-Cochrane Library, Embase via OVID, and Medline via OVID-were searched using subject headings and keywords. An independent librarian conducted the initial search and developed the strategy. A total of 569 publications were uploaded to Rayyan for blinded screening, yielding 42 studies. Meta-analysis was performed to determine prevalence rates for any DR, proliferative DR (PDR), diabetic macular oedema (DMO), and sight-threatening DR (STDR).
RESULTS
Global prevalence rates across the 7 IDF regions were: any DR 23 % (95 % CI: 20-26), PDR 6 % (95 % CI: 3-9), DMO 5 % (95 % CI: 4-6), and STDR 11 % (95 % CI: 9-14). Compared to 2015-2019 data, the rate of any DR decreased from 27 % to 23 %, while PDR increased from 1.4 % to 6 %. DMO rates remained stable (∼5%).
CONCLUSION
Global DR prevalence remains between 20 and 30%. However, variations in study design and regional practices limit trend interpretation. International screening guidelines, supported by advancing technology, are needed to produce robust epidemiological data for global Eye Health policy planning.
Copyright © 2025 The Author(s). Published by Elsevier B.V. All rights reserved.
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