A Review of Tc-labeled Tumor Metabolic Imaging Agents.

Yilin Li, Junbo Zhang

Journal: Mini reviews in medicinal chemistry 2022;22(12):1586-1596

PMID: 34355682

Abstract

In recent years, with the development of nuclear medicine imaging technology, radionuclide- labeled tumor imaging agents have shown unique advantages in the early diagnosis of tumors. Due to the relatively low cost of SPECT in the clinic with the convenient preparation and suitable properties of Tc, Tc-labeled tumor metabolic imaging agents prepared based on principles of tumor metabolism have gained considerable attention. This article briefly introduces the progress in the research of Tc-labeled glucose derivatives, amino acid derivatives, nucleotide derivatives, and other tumor metabolic imaging agents and proposes the prospects for the development of Tclabeled tumor metabolic imaging agents.

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Address: Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, P.R. China.
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