Phytochemicals toward Green (Bio)sensing.

Tina Naghdi, Shadab Faham, Tohid Mahmoudi, Nahid Pourreza, Raouf Ghavami, Hamed Golmohammadi

Journal: ACS sensors 2021;5(12):3770-3805

PMID: 33301670

Abstract

Because of numerous inherent and unique characteristics of phytochemicals as bioactive compounds derived from plants, they have been widely used as one of the most interesting nature-based compounds in a myriad of fields. Moreover, a wide variety of phytochemicals offer a plethora of fascinating optical and electrochemical features that pave the way toward their development as optical and electrochemical (bio)sensors for clinical/health diagnostics, environmental monitoring, food quality control, and bioimaging. In the current review, we highlight how phytochemicals have been tailored and used for a wide variety of optical and electrochemical (bio)sensing and bioimaging applications, after classifying and introducing them according to their chemical structures. Finally, the current challenges and future directions/perspective on the optical and electrochemical (bio)sensing applications of phytochemicals are discussed with the goal of further expanding their potential applications in (bio)sensing technology. Regarding the advantageous features of phytochemicals as highly promising and potential biomaterials, we envisage that many of the existing chemical-based (bio)sensors will be replaced by phytochemical-based ones in the near future.

Address: Nanosensor Bioplatforms Laboratory, Chemistry and Chemical Engineering Research Center of Iran, Tehran 14335-186, Iran.; Chemometrics Laboratory, Department of Chemistry, Faculty of Science, University of Kurdistan, Sanandaj 66177-15175, Iran.; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz 5166-15731, Iran.; Chemistry Department, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz 6153753843, Iran.

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