Perioperative Management of Novel Pharmacotherapies for Heart Failure and Pulmonary Hypertension.

Caroline R Gross, Robin Varghese, Zdravka Zafirova

Journal: Anesthesiology clinics 2024;42(1):117-130

PMID: 38278584

Full Text on Elsevier Science View on PubMed

Abstract

Heart failure (HF) and pulmonary hypertension (PH) are increasingly prevalent comorbidities in patients presenting for noncardiac surgery. The unique pathophysiology and pharmacotherapies associated with these syndromes have important perioperative implications. As new medications for HF and PH emerge, it is imperative that anesthesiologists and other perioperative providers understand their mechanisms of action, pharmacokinetics, and potential adverse effects. We present an overview of the novel HF and PH pharmacotherapies and strategies for their perioperative management.

Address: Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: [email protected].; Department of Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

DOI: 10.1016/j.anclin.2023.09.004