The Real Relevance of Nonacid Reflux in Pediatric Patients.

Suzanna Hirsch, Rachel Rosen

Journal: Journal of clinical gastroenterology 2023;57(8):754-759

PMID: 37436834

Full Text on Ovid Technologies, Inc. View on PubMed

Abstract

Gastroesophageal reflux (GER) is one of the most common presenting complaints to pediatric gastroenterologists, and a wide variety of symptoms in children are potentially attributable to typical or atypical GER. While reflux diagnosis and treatment paradigms classically have focused on targeting acid, there is a growing recognition of the prevalence and significance of nonacid GER in both children and adults. This review explores the role of nonacid reflux in pediatric patients, including definitions, associations with symptoms, pathophysiologic mechanisms, and treatment implications.

Address: Aerodigestive Center, Center for Motility and Functional Gastrointestinal Disorders, Division of Gastroenterology, Hepatology & Nutrition, Boston Children's Hospital, Boston, MA.

DOI: 10.1097/MCG.0000000000001868

Link outs

Free resources

Medical:

https://medlineplus.gov/gerd.html

Subscription / membership required

Full Text Sources:

MeSH Terms: Adult, Humans, Child, Gastroesophageal Reflux, Esophageal pH Monitoring, Prevalence