Chemistry and Bioactivity of the Genus Persea - A Review.

Carlos H Totini, Eric Umehara, Isabella M A Reis, João Henrique G Lago, Alexsandro Branco

Journal: Chemistry & biodiversity 2023;20(9):e202300947

PMID: 37539983

Abstract

This review provides the first comprehensive appraisal of bioactive compounds and their biological activities in Persea species from 1950 to 2023. Relevant articles from reputable databases, including PubMed, Web of Science, Science Direct and Google Scholar were collected, leading to the isolation of about 141 metabolite compounds, mainly flavonoids, terpenoids, fatty alcohols, lignoids, and γ-lactone derivatives. These compounds exhibit diverse biological activities, including insecticidal, antifeedant, nematicidal, antibacterial, antifungal, antiviral, cytotoxic, anti-inflammatory, and antioxidant properties. The review emphasizes the significant chemical and pharmacological potential of different Persea species, encouraging further research in various fields and medicine. Valuable insights into potential applications of Persea plants are provided.

© 2023 Wiley-VHCA AG, Zurich, Switzerland.

Address: Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, 09210-580, Santo Andre, SP, Brazil.; Departamento de Saúde, Universidade Estadual de Feira de Santana, 44036-900, Feira de Santana, BA, Brazil.

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