Shedding Light on Amoxicillin, Amoxicillin-clavulanate, and Cephalexin Dosing in Children from a Pharmacist's Perspective.

Diana Yu, Laura L Bio

Journal: Journal of the Pediatric Infectious Diseases Society 2022;11(12):594-602

PMID: 36112500

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Abstract

Selection of an antibiotic and dosing regimen requires consideration of multiple factors including microbiological data, site of infection, pharmacokinetics, and how it relates to the pharmacodynamic target. Given the multiple dosage regimens of amoxicillin with/without clavulanate and cephalexin, we review the principles of dose selection from a pharmacist's perspective.

© The Author(s) 2022. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: [email protected].

Address: Department of Pharmacy, Doernbecher Children's Hospital, Oregon Health and Science University, Portland, Oregon, USA.; Department of Pharmacy, Lucile Packard Children's Hospital Stanford, Palo Alto, California, USA.

DOI: 10.1093/jpids/piac105

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MeSH Terms: Child, Humans, Amoxicillin, Cephalexin, Pharmacists, Microbial Sensitivity Tests, Amoxicillin-Potassium Clavulanate Combination, Anti-Bacterial Agents, Clavulanic Acid