Structure, Function and Regulation of the Plasma Membrane Calcium Pump in Health and Disease.

Joachim Krebs

Journal: International journal of molecular sciences 2022;23(3):

PMID: 35162948

Abstract

In this review, I summarize the present knowledge of the structural and functional properties of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular expression of the different spliced isoforms of the four genes are regulated under normal and pathological conditions.

DOI: 10.3390/ijms23031027

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https://www.mdpi.com/resolver?pii=ijms23031027
https://pmc.ncbi.nlm.nih.gov/articles/pmid/3516294...
https://europepmc.org/abstract/MED/35162948

MeSH Terms: Cell Membrane, Gene Expression Regulation, Humans, Models, Molecular, Plasma Membrane Calcium-Transporting ATPases, Protein Conformation, RNA Splicing