Phytochemical Content and Potential Health Applications of Pecan [ (Wangenh) K. Koch] Nutshell.

Nohemí Del C Reyes-Vázquez, Laura A de la Rosa, Juan Luis Morales-Landa, Jorge Alberto García-Fajardo, Miguel Ángel García-Cruz

Journal: Current topics in medicinal chemistry 2022;22(2):150-167

PMID: 34986772

Abstract

BACKGROUND

The pecan nutshell contains phytochemicals with various biological activities that are potentially useful in the prevention or treatment of diseases, such as cancer, diabetes, and metabolic imbalances associated with heart diseases.

OBJECTIVE

The aim of this study is to update this topic by means of a literature review and include those studies that contribute to the knowledge of the chemical composition and biological activities of pecan nutshell, particularly those related to the therapeutic potential against some chronic degenerative diseases associated with oxidative stress.

METHODS

Exhaustive and detailed review of the existing literature was conducted using electronic databases.

CONCLUSION

The pecan nutshell is a promising natural product with pharmaceutical uses in various diseases. However, additional research related to the assessment of efficient extraction methods and characterization, particularly the evaluation of the mechanisms of action in new in vivo models, is necessary to confirm these findings and development of new drugs with therapeutic use.

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Address: Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco A. C. Subsede Noreste, 66629 Apodaca- 66629, Nuevo León, México.; Departamento de Ciencias Químico Biológicas, Instituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez-32310, Chihuahua, México.; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza-66450, Nuevo León, México.
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