Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.

Address: Epidemiology and Public Health Group, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.; University of Pittsburgh, Department of Epidemiology, Pittsburgh, PA, USA.; Department of Epidemiology and Biostatistics, Amsterdam UMC- Vrije Universiteit, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Biostatistics Center, Connecticut Convergence Institute for Translation in Regenerative Engineering, UConn Health, Farmington, CT, USA.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.; School fo Public Health University of Sydney, Sydney, NSW, Australia.; Medical School, University of Western Australia, Crawley, WA, Australia.; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Lübeck Interdisciplinary Plattform for Genome Analytics, Institutes of Neurogenetics and Cardiogenetics, University of Lübeck, Lübeck, Germany.; Cardiovascular Health Research Unit, Department of Medicine, and Department of Biostatistics, University of Washington, Seattle, WA, USA.; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK.; Biostatistics Department, Boston University School of Public Health, Boston, MA, USA.; Longitudinal Study Section, Translational Gerontology branch, National Institute on Aging, Baltimore, MD, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Bioinformatics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Rush Alzheimer's Disease Center & Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Medicine and Public Health, Rey Juan Carlos University, Madrid, Spain.; CIBER of Frailty and Healthy Aging (CIBERFES), Madrid, Spain.; Center for Demography of Health and Aging, University of Wisconsin-Madison, Madison, WI, USA.; School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.; Department of Orthopedics, University of Colorado, Aurora, CO, USA.; Department of Medicine/Geriatrics, University of Mississippi School of Medicine, Jackson, MS, USA.; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, 27516, USA.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health, Department of Endocrinology and Metabolism, Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health, Department of Endocrinology and Metabolism, Berlin, Germany.; Charité - Universitätsmedizin Berlin, BCRT - Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany.; Department of Internal Medicine, Section of Geriatric Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.; Wageningen University, Division of Human Nutrition, PO-box 17, 6700 AA, Wageningen, The Netherlands.; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.; Department of Epidemiology and Institute of Public Genetics, University of Washington, Seattle, WA, USA.; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.; Epidemiology and Biostatistics, Department of Public Health, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Geriatric Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Clinical and Molecular Osteoporosis Research Unit, Department of Orthopedics and Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden.; Center for Translational and Systems Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.; Department of Restorative Dentistry, Periodontology, Endodontology, and Preventive and Pediatric Dentistry, University Medicine Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; CIBER of Frailty and Healthy Aging (CIBERFES), Madrid, Spain.; Department of Geriatrics, Getafe University Hospital, Getafe, Spain.; CIBER of Frailty and Healthy Aging (CIBERFES), Madrid, Spain.; Department of Geriatrics, Hospital Virgen del Valle, Complejo Hospitalario de Toledo, Toledo, Spain.; CIBER of Frailty and Healthy Aging (CIBERFES), Madrid, Spain.; Professor of Public Policy, Georgetown University, Washington, DC, USA.; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Sahlgrenska University Hospital, Department of Drug Treatment, Gothenburg, Sweden.; Section of General Internal Medicine, Boston University School of Medicine, Boston, MA, USA.; Center on Aging, University of Connecticut Health, 263 Farmington Avenue, Farmington, CT, 06030, USA.; National Institute on Aging, Baltimore, MD, USA.; Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.; Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel.; Marcus Institute for Aging Research, Hebrew SeniorLife and Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Broad Institute of MIT & Harvard, Boston, MA, USA.; Epidemiology and Public Health Group, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK. [email protected].