A Review on Classification and Biological Activities of Alkaloids from the Genus Species.

Wen-Jun Wei, Xiao-Hui Chen, Tao Guo, Xiao-Qian Liu, Yi Zhao, Li-Li Wang, Jin-Xu Lan, Han-Wei Li, Yan-Po Si, Zhi-Min Wang

Journal: Mini reviews in medicinal chemistry 2021;21(3):336-361

PMID: 32912124

Abstract

Many plants in the genus Zanthoxylum, belonging to the Rutaceae family, are used as folk medicines for the treatment of various diseases, which have gained much attention for their phytochemical and pharmacological activity investigations. Alkaloids are the largest secondary metabolites with structurally diverse types found in this genus and they demonstrate a wide range of biological activities. The aim of this review is to provide a summary on the isolation, classification, and biological properties of alkaloids from Zanthoxylum species, which also will bring more attention to other researchers for further biological study on alkaloids for the new drug development.

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Address: School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, China.; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.; Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, New York, United States.

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