Dammarane triterpenoid glycosides in Bacopa monnieri: A review on chemical diversity and bioactivity.

Pamita Bhandari, Nitisha Sendri, Shinde Bhagatsing Devidas

Journal: Phytochemistry 2020;172():112276

PMID: 32058865

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Abstract

Bacopa monnieri (L.) is a reputed medicinal herb in traditional system of medicine of India, where it is used as nervine tonic to sharpen intellect and memory. This review discusses chemical characterization of dammarane triterpenoid glycosides which are well accepted for improvement in memory and for potential pharmacological activities. In addition, this review provides information on the chemical composition of specialized metabolites of B. monnieri and in the formulations by different analytical techniques. This comprehensive review covers literature up to 2019 with an emphasis on structural characterization of dammarane triterpenoid glycosides by spectroscopic techniques, chemical composition by analytical methods and pharmacological activities.

Address: Natural Product Chemistry & Process Development, CSIR-Institute of Himalayan Bioresource Technology, Palampur, India. Electronic address: [email protected].; Natural Product Chemistry & Process Development, CSIR-Institute of Himalayan Bioresource Technology, Palampur, India.

DOI: 10.1016/j.phytochem.2020.112276

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MeSH Terms: Bacopa, Glycosides, India, Plant Extracts, Triterpenes, Dammaranes