Three-year prospective randomized study of incidence of posterior capsule opacification in eyes treated with topical diclofenac and betamethasone.

Tadaharu Tsuchiya, Masahiko Ayaki, Takeo Onishi, Toshiyuki Kageyama, Shigeo Yaguchi

Journal: Ophthalmic research 2003;35(2):67-70

PMID: 12646745

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Abstract

PURPOSE

To investigate the incidence of posterior capsule opacification (PCO) in eyes treated with diclofenac sodium (DFNa) and betamethasone phosphate (BMS) ophthalmic solutions.

METHODS

A total of 200 eyes with silicone intraocular lens implantation were treated with topical agents for 3 months postoperatively. Twenty-six cases of the DFNa group and 34 of the BMS group met the criteria, and the severity of PCO was evaluated after 3 years.

RESULTS

The results of axial densitometry by Scheimpflug photography were 27.8 computer-compatible tapes (CCT) in the DFNa-treated group and 32.6 CCT in the BMS-treated group (p = 0.1539). Posterior capsulotomy was performed in 11.5% of the DFNa group and 17.6% of the BMS group (p = 0.8375). The photographic grading of PCO showed no difference.

CONCLUSION

The incidence of PCO in eyes treated with DFNa appears to be equal to that after BMS treatment.

Address: Department of Ophthalmology, Fujigaoka Hospital, Showa University School of Medicine, Yokohama, Japan.

DOI: 10.1159/000069127