Capillary Electrophoresis in Food and Foodomics.

Clara Ibáñez, Tanize Acunha, Alberto Valdés, Virginia García-Cañas, Alejandro Cifuentes, Carolina Simó

Journal: Methods in molecular biology (Clifton, N.J.) 2018;1483():471-507

PMID: 27645749

Abstract

Quality and safety assessment as well as the evaluation of other nutritional and functional properties of foods imply the use of robust, efficient, sensitive, and cost-effective analytical methodologies. Among analytical technologies used in the fields of food analysis and foodomics, capillary electrophoresis (CE) has generated great interest for the analyses of a large number of compounds due to its high separation efficiency, extremely small sample and reagent requirements, and rapid analysis. The introductory section of this chapter provides an overview of the recent applications of capillary electrophoresis (CE) in food analysis and foodomics. Relevant reviews and research articles on these topics are tabulated including papers published in the period 2011-2014. In addition, to illustrate the great capabilities of CE in foodomics the chapter describes the main experimental points to be taken into consideration for a metabolomic study of the antiproliferative effect of carnosic acid (a natural diterpene found in rosemary) against HT-29 human colon cancer cells.

Address: Foodomics Laboratory, CIAL, CSIC, c/Nicolas Cabrera, 9 Campus Cantoblanco, Madrid, 28049, Spain.; CAPES Foundation, Ministry of Education of Brazil, Brasília, DF, 70.040-020, Brazil.; Foodomics Laboratory, CIAL, CSIC, c/Nicolas Cabrera, 9 Campus Cantoblanco, Madrid, 28049, Spain. [email protected].

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