Potassium channels: complete and undistorted.

Alessandro Grottesi, Zara A Sands, Mark S P Sansom

Journal: Current biology : CB 2006;15(18):R771-4

PMID: 16169480

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Abstract

The recently determined structure of a mammalian voltage-gated potassium channel has important implications for our understanding of voltage-sensing and gating mechanisms in channels. It is also the first crystal structure of an overexpressed eukaryotic membrane protein.

Address: Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

DOI: 10.1016/j.cub.2005.08.054

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MeSH Terms: Kv1.2 Potassium Channel, Models, Molecular, Protein Conformation, Protein Structure, Tertiary