Individualized health-related quality of life instrument Measure Yourself Medical Outcome Profile (MYMOP) and its adaptations: a critical appraisal.

Sana Ishaque, Jeffrey A Johnson, Sunita Vohra

Journal: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2019;28(4):879-893

PMID: 30426277

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Plain Language Summary

Health-related quality of life has grown in its importance as an essential outcome for patient-centred research. Advances in medical research have resulted in prolonged survival for those with chronic diseases, making the patient’s experience vital to assessment of therapeutic effectiveness. The aim of this study was to critically appraise the measurement properties of MYMOP (Measure Yourself Medical Outcome Profile) and its adaptations. This study is a review of 16 studies evaluating four questionnaires (MYMOP and three adaptations: MYCaW, PSYCHLOPS, and MYMOP-P). Researchers reviewed the format, content and evidence of measurement properties for MYMOP, and its three adaptations. The review showed that MYMOP and its adaptations have been widely used in the evaluation of complementary therapies because of their excellent fit with individualised patient-centred approach. Therefore, individualised outcome assessment tools such as MYMOP are the way forward to personalised medicine approaches to tailor conventional therapies from patient perspective. Since validation is an ongoing process and considerable efforts have been put to develop and achieve sound psychometrics of these measures, authors conclude that researchers should further the validation of MYMOP and its adaptations before considering developing a new measure.

Abstract

BACKGROUND

Health-related quality of life (HRQL) is increasingly recognized for its importance in health research. As there is increasing recognition of the inter-individual difference in response to therapeutic interventions, it may be helpful to apply individualized measures of HRQL. The MYMOP is a commonly used example of such measures, although several adaptations have been developed.

OBJECTIVE

This review was conducted to identify adaptations of MYMOP, and evaluate the measurement properties of MYMOP and its adaptations.

METHODS

Adaptations were identified using MYMOP website and personal communication, supplemented by a SCOPUS search in April 2017. Bibliographies of included studies were hand-searched. COSMIN criteria were used to evaluate the measurement properties.

RESULTS

Sixteen studies were included in this review. Adaptations were developed to evaluate individualized therapies in cancer, psychiatry, and acupuncture. The included measures were MYMOP, measure yourself concern and wellbeing, psychological outcome profiles (PSYCHLOPS), and MYMOP-pictorial (MYMOP-P). The quality of the measurement properties varied; none of the included measures met all currently recommended quality criteria for measurement properties.

CONCLUSION

Current literature provides evidence that MYMOP and its adaptations offer individualized assessment of patient-centered outcomes, and thereby provide a means to understand heterogeneity of treatment effects. However, current recommendations for psychometric testing suggest further validation of these measures would be beneficial.

Address: School of Public Health, University of Alberta, Edmonton, AB, Canada.; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.; School of Public Health, University of Adelaide, Adelaide, SA, Australia.; School of Public Health, University of Alberta, Edmonton, AB, Canada.; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada. [email protected].

DOI: 10.1007/s11136-018-2046-6