Yellow pea-based pasta's impacts on the salt intake, glycemic parameters and oxidative stress in healthy individuals: a randomized clinical trial.

Mamoru Ito, Joto Yoshimoto, Sho Ishii, Tetsuya Maeda, Yu Wada, Yoshikazu Yonei, Mikiya Kishi, Takahiro Ono

Journal: Scientific reports 2024;14(1):23333

PMID: 39375402

Plain Language Summary

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Peas (Pisum sativum L.) are widely cultivated and recognised as a functional food due to their rich nutritional content, including proteins, minerals, dietary fibre, and polyphenols. These components provide antioxidant and anti-inflammatory benefits. This study investigated the effects of yellow pea-based pasta (YPP) on salt intake, glycaemic parameters, and oxidative stress markers in healthy adults consuming excessive salt based on Japanese dietary standards. In this open-label, parallel-group randomised controlled trial, participants (n=20) were divided into two groups: one consumed one YPP-based meal daily for four weeks, while the other followed their normal diet. Results showed that YPP intake: - improved several oxidative stress markers. - did not alter the participants’ sensitivity to saltiness. - had no effect on glycaemic parameters. Authors concluded that replacing one meal per day with YPP for four weeks may help reduce oxidative stress without affecting salt sensitivity or glycaemic control.

Abstract

Pea (Pisum sativum L.), a widely cultivated legumes globally, is attracting interest as a functional food owing to its antioxidant properties derived from nutritional components such as polyphenols. We previously reported that yellow pea-based pasta (YPP) aids in controlling blood glucose and enhances the sensitivity to saltiness. This study examined the antioxidant effect of YPP and its effects on the salt intake and postprandial blood glucose levels by simulating a real-life scenario. In this open, parallel-group, randomized controlled trial, 40 healthy adult men and women aged 20-65 years, whose salt intake exceeded the target salt equivalent level of the Japanese dietary intake standard, were allocated to the following groups (n = 20): the group consuming one serving of YPP per day and the group maintaining their regular daily dietary habits. The participants who were allocated to the YPP group showed significantly improved oxidative stress markers (BAP/d-ROMs ratio change: control =  - 0.11, YPP = 0.27, p = 0.044; lipid peroxide change: control = 0.11, YPP =  - 0.25, p < 0.001) than control participants. The effects on salt intake and blood glucose levels were limited. In conclusion, YPP may serve as a functional staple food that improves oxidative stress.

© 2024. The Author(s).

Address: Central Research Institute, Mizkan Holdings Co., Ltd., Handa-shi, Aichi, Japan. [email protected].; Central Research Institute, Mizkan Holdings Co., Ltd., Handa-shi, Aichi, Japan.; New Business Development, Mizkan Holdings Co., Ltd., Chuo-ku, Tokyo, Japan.; Anti-Aging Medical Research Center, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe-shi, Kyoto, Japan.; Ueno-Asagao Clinic, Taito-ku, Tokyo, Japan.
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