Effects of Omega-3 fatty acids supplementation and resistance training on skeletal muscle.

Yuta Uchida, Katsunori Tsuji, Eisuke Ochi

Journal: Clinical nutrition ESPEN 2024;61():189-196

PMID: 38777432

Free Full Text on Elsevier Science View on PubMed

Plain Language Summary

The age-related decline in muscle strength and skeletal muscle mass can impede the daily lives of older adults and make independent living difficult. The study aimed to investigate the effects of omega-3 fatty acids supplementation and resistance training on muscle strength and mass. This study was a systematic review and meta-analysis of five studies. Results showed that: - omega-3 fatty acids supplementation, when combined with resistance training, significantly improved muscle strength compared to the placebo-controlled group. - no significant effects were observed in terms of muscle mass. Authors concluded that omega-3 fatty acids and strength training could be a potential strategy in preventing sarcopenia.

Abstract

BACKGROUND & AIMS

The aim of this study was to investigate the omega-3 fatty acids supplementation, and resistance training on muscle strength and mass.

METHODS

A review was conducted by searching relevant randomized controlled trials investigating the effects of omega-3 fatty acids supplementation and resistance training on skeletal muscle strength and mass. Three experts independently performed a thorough examination of the literature database and conducted the systematic review and meta-analysis.

RESULTS

Four studies were ultimately included in the systematic review after screening. The results of the meta-analysis revealed that the supplementation of omega-3 fatty acids and resistance training significantly improved muscle strength compared to the placebo-controlled group. However, no significant effects were observed in the effect for muscle mass.

CONCLUSIONS

The interventions of omega-3 fatty acids supplementation and resistance training show promise as a countermeasure against muscular dysfunction. While further research is warranted to investigate its effects on skeletal muscle mass, the findings of this study hold implications for maintaining and/or improving the quality of life to elderly people.

Address: Faculty of Bioscience and Applied Chemistry, Hosei University, Tokyo, Japan.; Sports Research Center, Hosei University, Tokyo, Japan.; Faculty of Bioscience and Applied Chemistry, Hosei University, Tokyo, Japan; Graduate School of Sports and Health Studies, Hosei University, Tokyo, Japan. Electronic address: [email protected].

DOI: 10.1016/j.clnesp.2024.03.019

Patient Centred Factor

Mediators: Skeletal muscle

Clinical Imbalances

Structural Integrity and Musculoskeletal

Modifiable Lifestyle Factors

Diet Exercise and movement

Nutrition Evidence Keywords

Supplementation Polyunsaturated fatty acids Sarcopenia Omega-3 Fatty acids Resistance training Skeletal muscle

Bioactive Substances

Omega-3 fatty acids

Link outs

Free resources

Full Text Sources:

https://linkinghub.elsevier.com/retrieve/pii/S2405...

Medical:

https://medlineplus.gov/dietarysupplements.html

Subscription / membership required

Full Text Sources:

https://www.clinicalkey.com/content/playBy/pii?v=S...

MeSH Terms: Humans, Fatty Acids, Omega-3, Resistance Training, Muscle, Skeletal, Dietary Supplements, Muscle Strength, Randomized Controlled Trials as Topic, Quality of Life