Dietary Phytochemicals that Can Extend Longevity by Regulation of Metabolism.

Jie Shen, Jianying Shan, Lichao Zhong, Boying Liang, Dake Zhang, Motao Li, Hao Tang

Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 2022;77(1):12-19

PMID: 35025006

Abstract

Diet provides energy and nutrition for human survival, and also provides various joy of taste. Extensive studies have shown that the major components of diet, such as protein, carbohydrate and fat, play important roles in regulating aging and longevity. Whether other dietary ingredients can help prevent aging and extend longevity is a very interesting question. Here based on recent findings, we discussed dietary plant ingredients that can extend longevity by regulation of metabolism, targeting TRP channels, mitophagy, senescence pathways and circadian rhythms. Better understanding of the detailed effects and mechanisms of dietary ingredients on longevity regulation, would be helpful for developing new intervention tools for preventing aging and aging related diseases.

© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Address: Department of Biomedical Engineering, College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, 310018, China. [email protected].; Department of Biomedical Engineering, College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, 310018, China.; Department of Optoelectronic Information Science and Engineering, College of Science, Hangzhou Dianzi University, Hangzhou, 310018, China.

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