The traditional ethnic herb from China: a review of its phytochemistry and pharmacological activities.

Hong-Xia Tang, Wen-Bing Sheng, Xin-Yi Liu, Pei-Wu Cui, Li-Min Gong, Qing-Ling Xie, Wen-Mao Wang, Bin Li, Wei Wang, Xu-Dong Zhou

Journal: Pharmaceutical biology 2022;60(1):774-784

PMID: 35361038

Abstract

CONTEXT

(Linn.) Ohashi (Fabaceae) (), is a traditional herbal medicine used especially in China's ethnic-minority communities, such as the Zhuang, Dai, Li and Wa aeras. As an ethnic medicine, it has long been used to treat various diseases.

OBJECTIVE

This review summarised the phytochemical and pharmacological progress on from 1979 to October, 2021 by highlighting its chemical classification, structural features, pharmacological applications and folk applications to provide inspirations and suggestions for accelerating further research of this traditional phytomedicine.

METHODS

The information on in this article has been obtained using these multiple scientific databases including Scifinder, Web of Science, ScienceDirect, Wiley, ACS publications, Springer, PubMed, China Knowledge Resource Integrated Database from the China National Knowledge Infrastructure (CNKI), Google Scholar and Baidu Scholar. Some information was also collected from classic literature on traditional Chinese medicines.

RESULTS

More than 70 compounds have been isolated and reported from to date by the comprehensive analysis of the current literature. A large number of traditional uses and pharmacological studies have exhibited diversified bioactivities of various extracts and its metabolites, including anti-inflammatory, antimicrobial, anti-hepatitis B virus, hepatoprotective, insecticidal, etc.

CONCLUSIONS

As a famous traditional medicine with a long history, has various medicinal uses and some of them have been supported by modern pharmacological researches. Further detailed studies on the action mechanisms, pharmacodynamics and structure-function relationships of single compounds or active constituents from are also required.

Address: TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, P.R. China.; Meicha Technology Research Center, Hunan Qiankun Biotechnology Co., Ltd., Zhangjiajie, Hunan, P.R. China.
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