Potassium-rich diet and risk of stroke: updated meta-analysis.

L D'Elia, C Iannotta, P Sabino, R Ippolito

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 2015;24(6):585-7

PMID: 24780514

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Abstract

Recently a few prospective population studies provided additional and heterogeneous information concerning the reported statistical associations between potassium (K) intake and stroke risk. Therefore, we updated our previous meta-analysis of K intake and risk of cerebrovascular events. Three studies were added to the previous analysis, and the results of the comparison between the event rate in the two extreme categories of K intake were used. Pooled analysis of 14 cohorts (overall 333,250 participants and 10,659 events) showed an inverse and significant association between K intake and risk of stroke (Relative Risk: 0.80; 95% CI: 0.72-0.90). Our results indicated a favorable effect of higher K intake on risk of stroke. These results confirm the appropriateness of worldwide recommendations for a population increased consumption of potassium-rich foods to prevent cardiovascular disease.

Address: Department of Clinical Medicine and Surgery, ESH - Excellence Center for Hypertension, "Federico II" University of Naples Medical School, Naples, Italy. Electronic address: [email protected].; Department of Clinical Medicine and Surgery, ESH - Excellence Center for Hypertension, "Federico II" University of Naples Medical School, Naples, Italy.

DOI: 10.1016/j.numecd.2014.03.001

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MeSH Terms: Cerebrovascular Disorders, Cohort Studies, Evidence-Based Medicine, Female, Health Promotion, Humans, Hypertension, Male, Patient Compliance, Potassium Deficiency, Potassium, Dietary, Prospective Studies, Recommended Dietary Allowances, Risk, Sex Characteristics, Stroke