New and old approaches to nutritional management of acute and chronic glomerulonephritis.

Ramy M Hanna, Rebecca S Ahdoot, Connie M Rhee, Ekamol Tantisattamo, Fawaz Al Ammar, Kamyar Kalantar-Zadeh

Journal: Current opinion in nephrology and hypertension 2022;32(1):76-80

PMID: 36444665

Abstract

PURPOSE OF REVIEW

It has been well published that a low protein diet (0.6-0.8 g/kg/day) is optimal for nutritional management of chronic kidney disease and with care be used without inducing protein malnutrition.

RECENT FINDINGS

Though care with this approach must be demonstrated in patients with end-stage renal disease and with prominent protein energy wasting, another category of renal patient exists for whom dietary recommendations need more exploration. The Kidney Disease Improving Global Outcomes consortium, actually identifies renal disease as those patients with reduced filtration and those with excessive proteinuria excretion. Proteinuria, indeed, has proven to be a serious marker predisposing renal patients to atherosclerotic heart disease, venous thromboembolism, cerebrovascular accidents, and overall mortality. We discuss what is known about nutritional strategies to curb proteinuria and control inflammation in the setting of glomerulonephritis.

SUMMARY

While this area of management of a set of conditions maybe nascent, it has the potential to provide incredible breakthroughs in nutritional management of auto immune diseases of the kidney specifically and the body writ large.

Address: Harold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, California, United States.; Nephrology Section, Department of Medicine, Tibor Rubin Veterans Affairs Medical Center, Veterans Affairs Long Beach Healthcare System, Long Beach, California, United States.; Multi-Organ Transplant Center, Section of Nephrology, Department of Internal Medicine, William Beaumont Hospital, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan, United States.; Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Lundquist Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States.

DOI: 10.1097/MNH.0000000000000855

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MeSH Terms: Humans, Glomerulonephritis, Chronic Disease, Kidney, Kidney Failure, Chronic, Proteinuria