International Alliance of Urolithiasis (IAU) guidelines on the metabolic evaluation and medical management of urolithiasis.

Julian Veser, Kemal Sarica, Hans-Göran Tiselius, Zhangqun Ye, Liyuan Zhang, Zhankui Jia, Martino Marangella, Kunjie Wang, Michelle J Semins, Christian Türk, Yaoliang Deng, Cristian Fiori, Wei Zhu, Ben H Chew, Margaret S Pearle, Domenico Prezioso, Agnieszka Pozdzik, Daron Smith, Kristina L Penniston, William G Robertson, Guohua Zeng, Michael Straub, Tzevat Tefik

Journal: Urolithiasis 2022;51(1):4

PMID: 36454329

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Abstract

The aim of this study was to construct the fourth in a series of guidelines on the treatment of urolithiasis by the International Alliance of Urolithiasis (IAU) that by providing a clinical framework for the metabolic evaluation, prevention, and follow-up of patients with urolithiasis based on the best available published literature. All recommendations were summarized following a systematic review and assessment of the literature in the PubMed database from January 1976 to June 2022. Each generated recommendation was graded using a modified GRADE methodology. Guideline recommendations were developed that addressed the following topics: initial evaluation, metabolic testing, dietary measures, medical management, and follow-up of recurrent stone formers. It was emphasized by the Panel that prevention of new stone formation is as important as the surgical removal of the stones. Although general preventive measures may be effective in reducing stone recurrence rates in some patients, specific medical and dietary management should be well considered and eventually applied in an individualized manner based on the outcomes of metabolic work-up, stone analysis and some certain patient related factors. A detailed follow-up of each case is essential depending on the metabolic activity of each individual patient.

Address: Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. [email protected].; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Lithoscreen Service, Over, CB24 5NE, Cambridge, UK.; Department of Urology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.; Department of Urology, Westmoreland Street Hospital, University College Hospital London, London, UK.; Nephrology and Dialysis Department, Kidney Stone Clinic, Hôpital Universitaire Brugmann, Brussels, Belgium.; Faculty of Medicine, Université Libre de Bruxelles (ULB), Brussels, Belgium.; Department of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.; Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University, Naples, Italy.; Department of Urology, UT Southwestern Medical Center, Dallas, TX, USA.; Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna General Hospital, Vienna, Austria.; Division of Urology, Department Of Oncology, School of Medicine, University of Turin, San Luigi Hospital, Orbassano, Turin, Italy.; Department of Urology, First Affiliated Hospital of Guangxi Medical University, Nanning, China.; Department of Urology, Technical University Munich, Munich, Germany.; Sisters of Charity Hospital Vienna, Vienna, Austria.; Department of Urology, West Virginia University, Wheeling, WV, USA.; Department of Urology, Institute of Urology, Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, Chengdu, China.; Fondazione Scientifica Ospedale Mauriziano Onlus, Turin, Italy.; Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Department of Urology, Huazhong University of Science and Technology Union Shenzhen Hospital (Nanshan Hospital), Shenzhen, China.; Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.; Department of Urology, Karolinska Institutet - Huddinge Campus, Stockholm, Sweden. [email protected].; Department of Urology, Medical School, Biruni University, Istanbul, Turkey. [email protected].

DOI: 10.1007/s00240-022-01387-2

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https://dx.doi.org/10.1007/s00240-022-01387-2

MeSH Terms: Humans, Urolithiasis