Perspectives on the Therapeutic Effects of Pelvic Floor Electrical Stimulation: A Systematic Review.

Alessandra Durazzo, Massimo Lucarini, Ana Lúcia Carneiro Sarmento, Bruno Silva Sá, Andreanne Gomes Vasconcelos, Daniel Dias Rufino Arcanjo, José Roberto de Souza de Almeida Leite, Hugo Alves Sousa, Selma Aparecida Souza Kückelhaus

Journal: International journal of environmental research and public health 2022;19(21):14035

PMID: 36360918

Abstract

Pelvic, perineal, and nervous lesions, which derive principally from pregnancy and childbirth, may lead to pelvic floor dysfunctions, such as organ prolapses and lesions in the nerves and muscles due to muscle expansion and physiology. It is estimated that 70% of women affected by this clinical picture have symptoms that do not respond to the classical treatments with antimuscarinic and anticholinergic drugs. Therefore, resorting to efficient alternatives and less invasive methods is necessary to assist this public health problem that predominantly affects the female population, which is more susceptible to the risk factors. This study aimed to perform an updated and comprehensive literature review focused on the effects of pelvic floor electrical stimulation, considering new perspectives such as a correlation between electric current and site of intervention and other molecular aspects, different from the present reviews that predominantly evaluate urodynamic aspects. For that purpose, PubMed and ScienceDirect databases were used to perform the search, and the method was applied. With well-researched therapeutic effects, electrical stimulation induced promising results in histological, nervous, and molecular evaluations and spinal processes, which showed beneficial results and revealed new perspectives on ways to evoke responses in the lower urinary tract in a non-invasive way. Thus, it is possible to conclude that this type of intervention may be a non-invasive alternative to treat pelvic and perineal dysfunctions.

Address: Research Center in Applied Morphology and Immunology (NuPMIA), Faculty of Medicine (FM), University of Brasília (UnB), Brasília 70910-900, DF, Brazil.; Department of Biomedicine, University Centre of the Federal District (UDF), Brasília 70390-045, DF, Brazil.; Laboratory of Functional and Molecular Studies in Physiopharmacology (LAFMOL), Department of Biophysics and Physiology, Federal University of Piauí (UFPI), Teresina 64049-550, PI, Brazil.; CREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy.
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