The Use of Antioxidants in the Prevention and Treatment of Noise-Induced Hearing Loss.

Haley Hullfish, Luis P Roldan, Michael E Hoffer

Journal: Otolaryngologic clinics of North America 2022;55(5):983-991

PMID: 36088150

Full Text on Elsevier Science View on PubMed

Abstract

As of today, there are no therapeutic measures for the prevention or treatment of noise-induced hearing loss (NIHL). The current preventative measures, including avoidance and personal protective hearing equipment, do not appear to be sufficient because there is an increasing number of people with NIHL, especially in the adolescent population. Therefore, we must find a therapy that prevents the impact of noise on hearing. Antioxidants are a promising option in preventing the damaging effects of noise by targeting free radicals but further studies are needed to confirm their efficacy in humans.

Address: Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Miami, FL 33136, USA. Electronic address: [email protected].; Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Miami, FL 33136, USA.; Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Miami, FL 33136, USA; Department of Neurological Surgery, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Miami, FL 33136, USA.

DOI: 10.1016/j.otc.2022.06.006

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MeSH Terms: Acetylcysteine, Adolescent, Antioxidants, Hearing, Hearing Loss, Noise-Induced, Humans, Noise