Fracture Risk in Vegetarians and Vegans: the Role of Diet and Metabolic Factors.

Anna R Ogilvie, Brandon D McGuire, Lingqiong Meng, Sue A Shapses

Journal: Current osteoporosis reports 2022;20(6):442-452

PMID: 36129610

Abstract

PURPOSE OF REVIEW

There is strong evidence that poor dietary intake of certain micro- and macro-nutrients can negatively affect bone health. It is unclear if diet is the primary culprit for poor bone health in the vegan population.

RECENT FINDINGS

Plant-based diets are gaining public interest since they may improve metabolic health. Studies that examine vegetarians and vegans together show a lower bone mineral density (BMD), but not always increased fracture risk compared to omnivores. However, vegans consistently have higher risk of fracture at multiple bone sites, especially at the hip. There is higher fracture risk in vegans which may be due to calcium and vitamin D intake, as well as amount of dietary protein and quality. Other nutrients (B vitamins, Se, Zn, Fe, iodine) or physiological factors (lower body mass index, microbiome, or endocrine profile) may also play a role but have not been examined and require further study.

© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Address: Department of Nutritional Sciences, Rutgers University, New Brunswick, NJ, USA.; Institute of Food, Nutrition, and Health, Rutgers University, New Brunswick, NJ, USA.; Department of Nutritional Sciences, Rutgers University, New Brunswick, NJ, USA. [email protected].; Institute of Food, Nutrition, and Health, Rutgers University, New Brunswick, NJ, USA. [email protected].; Department of Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA. [email protected].

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