Repeatability of a Scheimpflug tonometer to measure biomechanical parameters before and after myopic refractive surgery.

Farhad Hafezi, Jia Zhang, Nan-Ji Lu, Jos J Rozema, Mark Hillen, Nikki Hafezi, Carina Koppen

Journal: Journal of cataract and refractive surgery 2022;48(9):1057-1062

PMID: 35171143

Abstract

PURPOSE

To assess the repeatability of several corneal biomechanical parameters with a Scheimpflug tonometer (Corvis ST) in myopic eyes and eyes that underwent transepithelial photorefractive keratectomy (transPRK), small-incision lenticule extraction (SMILE), or femtosecond laser-assisted in situ keratomileusis (FS-LASIK) surgery.

SETTING

Eye Hospital of Wenzhou Medical University, Wenzhou, China.

DESIGN

Prospective randomized controlled study.

METHODS

315 eyes from 315 patients (135 myopes, 58 post-transPRK, 52 post-SMILE, and 70 post-FS-LASIK) were included. 3 consecutive scans were performed to evaluate the repeatability of the 40 parameters examined.

RESULTS

315 eyes were included. In all eyes, the coefficient of variation (CoV) for intraocular pressure (IOP) and biomechanical-corrected IOP (bIOP) ranged from 7.29% to 9.47% and 6.11% to 7.75%, respectively; the CoV of pachymetry was <0.8%. The intraclass correlation coefficient of Corvis Biomechanical Index-Laser Vision Correction (LVC) was 0.680 for post-transPRK, 0.978 for post-SMILE, and 0.911 for post-FS-LASIK. The CoV of Stress-Strain Index (SSI) was 204.93% for post-transPRK, 91.92% for post-SMILE, and 171.72% for post-FS-LASIK. The CoV of the 6 clinically important dynamic corneal response parameters ranged from 2.0% to 7.8% for myopia, 1.8% to 11.1% for post-transPRK, 2.1% to 8.7% for post-SMILE, and 1.8% to 8.8% for post-FS-LASIK.

CONCLUSIONS

Excellent intrameasurement repeatability of IOP, bIOP, and pachymetry was observed in all groups; SSI measurement in post-LVC corneas displayed more variation. Caution is warranted when assessing SSI in post-LVC corneas for the purpose of diagnosing iatrogenic ectasia or evaluating biomechanical remodeling of postoperative refractive corneas.

Copyright © 2022 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.

Address: From the School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China (Lu, F. Hafezi, Zhang); Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium (Lu, Rozema, N. Hafezi, Koppen); Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium (Lu, Rozema, N. Hafezi, Koppen); ELZA Institute, Dietikon, Switzerland (Lu, F. Hafezi, Hillen, N. Hafezi); Ocular Cell Biology Group, Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Zurich, Switzerland (F. Hafezi); Department of Ophthalmology, University of Southern California, Los Angeles, California (F. Hafezi); Faculty of Medicine, University of Geneva, Geneva, Switzerland (F. Hafezi).
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