More than forty years of nucleic acid structural science.

Gary N Parkinson, Helen Berman

Journal: Bioorganic & medicinal chemistry 2022;69():116887

PMID: 35749839

Full Text on Elsevier Science View on PubMed

Abstract

As scientists who have worked with Stephen Neidle over many years and stages of his career, we present our perspective of his contributions to nucleic acid structural science. We trace some of the highlights of his research on nucleic acid drug interactions and the unique insights about the importance of hydration.

Address: Department of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy, London WC1N 1AX, UK. Electronic address: [email protected].; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address: [email protected].

DOI: 10.1016/j.bmc.2022.116887

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MeSH Terms: DNA, Nucleic Acid Conformation, Nucleic Acids