Bioactivities and Mechanism of Actions of : A Comprehensive Review.

Xiaoyu Xu, Cheng Zhang, Ning Wang, Yu Xu, Guoyi Tang, Lin Xu, Yibin Feng

Journal: Oxidative medicine and cellular longevity 2022;2022():6293355

PMID: 36160715

Abstract

has a long history of being consumed as a functional food and medicinal herb for preventing and managing diseases. The phytochemical studies revealed that contained abundant bioactive compounds, such as bibenzyls, polysaccharides, flavonoids, and alkaloids. The experimental studies showed that and its bioactive compounds exerted multiple biological properties like antioxidant, anti-inflammatory, and immune-regulatory activities and showed various health benefits like anticancer, antidiabetes, cardiovascular protective, gastrointestinal modulatory, hepatoprotective, lung protective, and neuroprotective effects. In this review, we summarize the phytochemical studies, bioactivities, and the mechanism of actions of , and the safety and current challenges are also discussed, which might provide new perspectives for its development of drug and functional food as well as clinical applications.

Copyright © 2022 Xiaoyu Xu et al.

Address: School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.; Engineering Research Center of Shanghai Colleges for TCM New Drug Discovery, Shanghai 201203, China.
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