Unsolved problems and new medical approaches to otitis media.

Nicola Principi, Susanna Esposito

Journal: Expert opinion on biological therapy 2021;20(7):741-749

PMID: 32178551

Abstract

INTRODUCTION

Otitis media (OM) is a spectrum of infectious and inflammatory diseases that involve the middle ear. It includes acute otitis media (AOM), otitis media with effusion (OME) and chronic suppurative otitis media (CSOM).

AREAS COVERED

This manuscript discusses some of the emerging and unsolved problems regarding OM, and some of the newly developed prophylactic and therapeutic medical measures.

EXPERT OPINION

In recent years, considerable progress in the knowledge of OM physiopathology has been made. However, although extremely common, diseases included under OM have not been adequately studied, and many areas of development, evolution and possible treatments of these pathologies are not defined. It is necessary that these deficiencies be quickly overcome if we want to reduce the total burden of a group of diseases that still have extremely high medical, social and economic relevance.

Address: Emeritus of Pediatrics, Università Degli Studi Di Milano , Milan, Italy.; Pediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma , Parma, Italy.

DOI: 10.1080/14712598.2020.1740677

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https://www.tandfonline.com/doi/10.1080/14712598.2...

MeSH Terms: Acetylcysteine, Anti-Bacterial Agents, Biofilms, Child, Humans, Otitis Media, Otitis Media with Effusion, Otitis Media, Suppurative, Pneumococcal Vaccines, Streptococcus