What's new in the treatment of advanced prostate cancer?

C N Sternberg

Journal: European journal of cancer (Oxford, England : 1990) 2003;39(2):136-46

PMID: 12509944

Full Text on Elsevier Science View on PubMed

Abstract

Increased insight into the biology of prostate cancer and the emergence of new therapeutic strategies and chemotherapeutic agents has changed approaches in treating patients with advanced prostate cancer. After secondary hormonal manipulations, new approaches include: second-line hormonal therapy, chemotherapy, immunotherapy with granulocyte macrophage-colony stimulating factor (GM-CSF) therapy, dendritic cell therapy, gene vaccination therapy, inhibition and/or blockade of growth factor receptors or growth factor receptor pathways, inhibition of neo-angiogenesis and inhibition of invasion and metastases.

Address: Chief, Department of Medical Oncology, San Camillo-Forlanini Hospital, Vincenzo Pansadoro Foundation, Via Aurelia 559, 00165 Rome, Italy. [email protected]

DOI: 10.1016/s0959-8049(02)00665-2

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MeSH Terms: Angiogenesis Inhibitors, Antibodies, Monoclonal, Antineoplastic Agents, Cancer Vaccines, Diphosphonates, Genetic Therapy, Growth Inhibitors, Humans, Immunotherapy, Male, Prostatic Neoplasms, Sulindac, Vitamin D