The nuclear pore complex: oily spaghetti or gummy bear?

Karsten Weis

Journal: Cell 2007;130(3):405-7

PMID: 17693250

Free Full Text on Elsevier Science View on PubMed

Abstract

In this issue, Frey and Görlich (2007) provide new insight into the selective barrier that controls protein traffic through the nuclear pore complex. They show that a single protein domain of the nuclear pore protein Nsp1 can form a hydrogel that allows highly selective access of nuclear transport receptors and their cargos, but rejects other proteins of similar size.

Address: Department of Molecular and Cell Biology, Division of Cell and Developmental Biology, University of California Berkeley, Berkeley, CA 94720-3200, USA. [email protected]

DOI: 10.1016/j.cell.2007.07.029

Link outs

Free resources

Full Text Sources:

https://linkinghub.elsevier.com/retrieve/pii/S0092...

Molecular Biology Databases:

https://www.yeastgenome.org/reference/17693250

MeSH Terms: Calcium-Binding Proteins, Humans, Nuclear Pore, Nuclear Pore Complex Proteins, Nuclear Proteins, Protein Transport, Saccharomyces cerevisiae Proteins