Advances of stable isotope technology in food safety analysis and nutrient metabolism research.

Wei Xia, Xiangjun Fang, Yuan Gao, Weijie Wu, Yanchao Han, Ruiling Liu, Hailong Yang, Hangjun Chen, Haiyan Gao

Journal: Food chemistry 2023;408():135191

PMID: 36527919

Full Text on Elsevier Science View on PubMed

Abstract

Food quality, safety, and the regulatory metabolism of food nutrients in cells are primary factors in determining human health. However, residues of undesirable or hazardous compounds in food products and dysregulation in the nutrient metabolism inevitably occur occasionally. For years, chromatography-mass spectrometry technology has been recognized as an essential research tool in food analysis and nutrient metabolism research, and it is more accurate and robust when coupled with stable isotopes. In this study, we summarize the applications of stable isotope technology in the quantification of contaminant residues (pesticides, veterinary drugs, mycotoxins, polycyclic aromatic hydrocarbons, and other hazardous compounds) in foods and in the nutrients (glucose, lipids, amino acids and proteins) metabolism research. The aim of this review was to serve as a reference for providing effective analysis techniques for protecting food quality and human health, and to pave the way for the broader application of stable isotope technology.

Address: Key Laboratory of Post-Harvest Handing of Fruits, Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology Research of Zhejiang Province, Key Laboratory of Postharvest Preservation and Processing of Fruits and Vegetables, China National Light Industry, Food Science Institute, Zhejiang Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Hangzhou 310021, China.; College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China. Electronic address: [email protected].; Key Laboratory of Post-Harvest Handing of Fruits, Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology Research of Zhejiang Province, Key Laboratory of Postharvest Preservation and Processing of Fruits and Vegetables, China National Light Industry, Food Science Institute, Zhejiang Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Hangzhou 310021, China. Electronic address: [email protected].; Key Laboratory of Post-Harvest Handing of Fruits, Key Laboratory of Fruits and Vegetables Postharvest and Processing Technology Research of Zhejiang Province, Key Laboratory of Postharvest Preservation and Processing of Fruits and Vegetables, China National Light Industry, Food Science Institute, Zhejiang Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Hangzhou 310021, China. Electronic address: [email protected].

DOI: 10.1016/j.foodchem.2022.135191

Link outs

Subscription / membership required

Full Text Sources:

https://linkinghub.elsevier.com/retrieve/pii/S0308...

MeSH Terms: Humans, Hazard Analysis and Critical Control Points, Isotopes, Mass Spectrometry, Proteins, Nutrients, Food Analysis, Isotope Labeling