Participation in a clinical trial is associated with lower mortality but not lower risk of HF hospitalization in patients with heart failure: observations from the ESC EORP Heart Failure Long-Term Registry.

Address: Department of Cardiology, Laiko General Hospital, Athens, Greece.; Unit of Cardiology, Department of Medicine, Karolinska Institutet, Solna, S1:02, 171 76 Stockholm, Sweden.; Unidad de Insuficiencia Cardiaca Avanzada y Trasplante Cardiaco, Complexo Hospitalario Universitario A Coruna, CHUAC, INIBIC, UDC, CIBERCV, La Coruna, Spain.; Department of Cardiology (CVK), Berlin Institute of Health Center for Regenerative Therapies (BCRT), and German Centre for Cardiovascular Research (DZHK) Partner Site Berlin, Charité Universitätsmedizin, Berlin, Germany.; Heart Research Institute, Sydney, Australia.; Emergency Institute for Cardiovascular Diseases 'Prof. C.C. Iliescu', University of Medicine Carol Davila, Bucharest, Romania.; Heart Failure Unit, Department of Cardiology, University Hospital Attikon, National and Kapodistrian University of Athens, Athens, Greece.; Division of Cardiology, Murska Sobota, Murska Sobota and Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.; King's College Hospital, London, UK.; Department of Anesthesia-Burn-Critical Care, UMR 942 Inserm-MASCOT, University of Paris, APHP Saint Louis Lariboisière University Hospitals, Paris, France.; Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.; Clinical Cardiology, IRCCS Policlinico San Donato Milanese, Milan, Italy.; IRCCS San Raffaele Pisana, Rome, Italy.; Clinic of Cardiology, University Hospital, Zürich, Switzerland.; Faculty of Medicine, University of Belgrade, Belgrade, Serbia.; Department of Human Science and Promotion of Quality of Life, San Raffaele Open University of Rome, Rome, Italy.; Cardiopulmonary Department, IRCCS San Raffaele, Rome, Italy.; ANMCO Research Center, Heart Care Foundation, Florence, Italy.