Diagnostic accuracy for alternative cervical cancer screening strategies: A systematic review and meta-analysis.

Narmin Karisani, Soheila Aminimoghaddam, Maryam Kashanian, Hamid Reza Baradaran, Yousef Moradi

Journal: Health care for women international 2024;45(3):323-362

PMID: 35084291

Abstract

We performed a systematic review and meta-analysis to evaluate the accuracy of screening cervical cancer tests as alternative standalone methods. The combined estimates of sensitivity of visual inspection with acetic acid, visual inspection with lugol's iodine, conventional pap smear, liquid-based cytology, High risk HPV testing by clinician, High risk HPV testing by self- sampling, cervicography were 64%, 80%, 55%, 70%, 70% and 67% respectively; the combine values of specificity of these screening strategies were 88%, 88%, 96%, 59%, 94%, and 95% respectively. Our findings draw attention to an attractive opinion to facilitate the collection of specimens for DNA HPV by patients in settings where they don't have access to a regular screening programs.

Address: Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Akbarabadi Teaching Hospital, Tehran, Iran.; Gynecologist Oncologist, Iran University of Medical Sciences, Tehran, Iran.; Ageing Clinical & Experimental Research Team, Institute of Applied Health Sciences, Aberdeen, Scotland.; Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.

DOI: 10.1080/07399332.2021.1998059

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MeSH Terms: Humans, Female, Uterine Cervical Neoplasms, Early Detection of Cancer, Vaginal Smears, Papillomavirus Infections, Sensitivity and Specificity, Papanicolaou Test, Mass Screening, Acetic Acid, Papillomaviridae, Specimen Handling, Uterine Cervical Dysplasia, Iodides