Important drug interactions and reactions in dermatology.

Nancy Aria, C Lisa Kauffman

Journal: Dermatologic clinics 2003;21(1):207-15, ix

PMID: 12622282

Full Text on Elsevier Science View on PubMed

Abstract

A constantly expanding pharmacological armamentarium increases the concern for serious drug interactions. This article discusses drug metabolism and how the cytochrome P-450 family facilitates drug biotransformation. Clinically significant drug interactions involving antifungal drugs, antibiotics, retinoids, and immunosuppressive agents, as well as topical anesthetics and various foods, are included.

Address: Georgetown University Medical Center, 3800 Reservoir Road NW 5-PHC Dermatology, Washington, DC 20007, USA.

DOI: 10.1016/s0733-8635(02)00071-2

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MeSH Terms: Anti-Infective Agents, Biotransformation, Cytochrome P-450 Enzyme System, Dermatologic Agents, Drug Interactions, Humans, Immunosuppressive Agents, Lidocaine, Lidocaine, Prilocaine Drug Combination, Pharmaceutical Preparations, Prilocaine