The effect of exercise training on serum concentrations of chemerin in patients with metabolic diseases: a systematic review and meta-analysis.

Damoon Ashtary-Larky, Alexei Wong, Sara Kashkooli, Delsa Mombaini, Nasrin Lamuchi-Deli, Reza Bagheri, Meysam Alipour, Julien S Baker, Amirhossein Ramezani Ahmadi

Journal: Archives of physiology and biochemistry 2023;129(5):1028-1037

PMID: 33651961

Full Text on Atypon View on PubMed

Abstract

CONTEXT

Elevated serum concentrations of chemerin is a significant factor in the development of metabolic disorders.

OBJECTIVE

This systematic review and meta-analysis evaluated the influence of exercise training on serum concentrations of chemerin in patients with metabolic diseases.

METHODS

Thirteen studies including 463 participants were included and analysed using a random-effects model to calculate weighted mean differences with 95% confidence intervals.

RESULTS

Results indicated that exercise training significantly decreased serum concentrations of chemerin in patients with metabolic diseases when compared with controls. Subgroup analysis showed that exercise training resulted in decreases in serum concentrations of chemerin in men, however, this was not significant in women. Moreover, subgroup analyses based on the type of exercise did not reveal differential effects on serum concentrations of chemerin.

CONCLUSION

Exercise training may produce improvements in serum concentrations of chemerin in patients with metabolic diseases. Further longer-term studies are needed to confirm these findings.

Address: Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.; Department of Exercise Physiology, University of Isfahan, Iran Isfahan.; Alimentary Tract Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Nutrition and Metabolic Disease Research center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Centre for Health and Exercise Science Research, Hong Kong Baptist University, Kowloon Tong, Hong Kong.; Department of Nutrition, School of Applied Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.; Department of Health and Human Performance, Marymount University, Arlington, TX, USA.

DOI: 10.1080/13813455.2021.1892149

Link outs

Free resources

Medical:

https://medlineplus.gov/metabolicdisorders.html

Other Literature Sources:

https://scite.ai/reports/33651961

Subscription / membership required

Full Text Sources:

https://www.tandfonline.com/doi/10.1080/13813455.2...

MeSH Terms: Male, Humans, Female, Obesity, Chemokines, Intercellular Signaling Peptides and Proteins, Exercise, Metabolic Diseases