Hand-sewn direct repair versus resection and hand-sewn anastomosis techniques for the reversal of diverting loop ileostomy after lower anterior rectal resection surgery: A randomized clinical trial.

Mohammad Reza Keramati, Seyed Mostafa Meshkati Yazd, Reza Shahriarirad, Seyed Mohsen Ahmadi Tafti, Alireza Kazemeini, Behnam Behboudi, Mohammad Sadegh Fazeli, Amir Keshvari

Journal: Journal of surgical oncology 2023;127(5):798-805

PMID: 36576493

Abstract

INTRODUCTION

Several techniques have been proposed for the closure of loop ileostomy. This is the first study comparing bowel function and outcomes of two different hand-sewn surgical techniques used for the closure of diverting protective loop ileostomy.

METHOD

In this prospective, randomized, double-blind clinical trial, 40 patients with a history of rectal cancer, low anterior resection, and diverting loop ileostomy who were candidates for ileostomy reversal were included and randomly assigned into two groups, hand-sewn direct repair of the ileal defect (group A) and resection and hand-sewn anastomosis of the ileum (group B).

RESULTS

The mean age of patients was 56.42 and 52.10 years in groups A and B, respectively. Regarding early postoperative period, group A developed earlier first gas passage (1.68 vs. 2.25 days, p = 0.041) and stool passage (2.10 vs. 2.80 days, p = 0.032). Group A also revealed shorter operating time (83.68 vs. 89.50 min, p = 0.040) and hospital stay (4.73 vs. 6.80 days, p = 0.001). None of the participants in both groups developed signs of bowel obstruction during the early and late postoperative follow-up period.

CONCLUSIONS

Direct hand-sewn repair for the closure of diverting loop ileostomy is a safe technique with better postoperative bowel function, oral diet tolerance, and less hospital stay compared to resection and hand-sewn anastomosis of the ileum.

© 2022 Wiley Periodicals LLC.

Address: Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran.; Colorectal Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

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