Evidence-based review of nonantibiotic urinary tract infection prevention strategies for women: a patient-centered approach.

Sabrina L Stair, Cristina J Palmer, Una J Lee

Journal: Current opinion in urology 2023;33(3):187-192

PMID: 36862100

Abstract

PURPOSE OF REVIEW

There is a growing interest in nonantibiotic prevention strategies for recurrent urinary tract infections (rUTIs). Our objective is to provide a focused, pragmatic review of the latest evidence.

RECENT FINDINGS

Vaginal estrogen is well tolerated and effective for preventing rUTI in postmenopausal women. Cranberry supplements at sufficient doses are effective in preventing uncomplicated rUTI. Methenamine, d -mannose, and increased hydration all have evidence to support their use, although the evidence is of somewhat variable quality.

SUMMARY

There is sufficient evidence to recommend vaginal estrogen and cranberry as first-line rUTI prevention strategies, particularly in postmenopausal women. Prevention strategies can be used in series or in tandem, based on patient preference and tolerance for side effects, to create effective nonantibiotic rUTI prevention strategies.

Address: Section of Urology and Renal Transplantation, Virginia Mason Medical Center, 1100 Ninth Avenue, C7-URO, Seattle, Washington, USA.

DOI: 10.1097/MOU.0000000000001082

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https://medlineplus.gov/urinarytractinfections.htm...

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MeSH Terms: Female, Humans, Urinary Tract Infections, Complementary Therapies, Methenamine, Estrogens, Patient-Centered Care, Recurrence