Ten-Year Follow-Up of Orbital Volume Augmentation With Calcium Hydroxyapatite Filler in Postenucleation Socket Syndrome.

Alessandra Di Maria, Vanessa Ferraro, Nicoletta Trenti, Emanuela Morenghi, Alessandro Gaeta, Paolo Vinciguerra, Filippo Confalonieri

Journal: Ophthalmic plastic and reconstructive surgery 2024;40(1):49-54

PMID: 37581879

Abstract

PURPOSE

To describe the efficacy and persistence of injectable calcium hydroxyapatite (CAHY) to correct orbital volume deficit in postenucleation socket syndrome.

METHODS

An observational study was conducted as a clinical review of all patients in the authors' practice who received injectable CAHY placed in the extraconal and intraconal space to increase orbital volume with a 10-year follow up. The amount of CAHY to be injected was defined according to the degree of orbital volume deficit. Patients previously treated with radiotherapy or with a conjunctival fornix insufficient to accommodate the external prosthesis were excluded. All the patients with at least 10 years of follow up were included in the study.

RESULTS

Thirty-one postenucleation socket syndrome patients received injectable CAHY for orbital volume augmentation, with a 10-year follow up. The mean amount of preoperative relative enophthalmos measured by Hertel's exophthalmometry was 14.16 ± 2.15. An increase in the mean orbital volume of 3.35 ± 0.91 at 6 months and 2.97 ± 1.35 at 10 years was obtained. The mean follow-up was 219 ± 18 months (range, 184-240). Patients demonstrated clinical and cosmetic improvement that was observed to continue for 10 years. The complications were peribulbar ecchymosis, 2 extrusions of the internal prosthesis, and 2 ptosis.

CONCLUSIONS

Injectable CAHY provides safe, simple, repeatable, and cost-effective technique to treat volume deficiency in the enophthalmic orbit in the long term. The volume augmentation obtained with this semipermanent filler demonstrated a lasting effect in the orbit with negligible loss of volume at 10 years.

Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc.

Address: Department of Ophthalmology, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.; Department of Radiology, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Internal Medicine and Medical Specialties (DIMI), Università di Genova, Genova GE, Italy.; Department of Ophthalmology, Center for Eye Research and Innovative Diagnostics, Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Ophthalmology, Oslo University Hospital, Oslo, Norway.
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