Disorders of bone and bone mineral metabolism.

Monica Komoroski, Nasrin Azad, Pauline Camacho

Journal: Handbook of clinical neurology 2014;120():865-87

PMID: 24365358

Abstract

Metabolic bone disorders are very common in the general population and untreated, they can cause a variety of neurologic symptoms. These diseases include osteoporosis, vitamin D deficiency, Paget's disease, and alterations in calcium, phosphorus, and magnesium metabolism. Diagnosis is made through analysis of metabolic bone blood chemistries as well as radiologic studies such as dual energy X-ray absorptiometry (DXA) scans, bone scans, and X-rays. Treatment options have advanced significantly in the past decade for osteoporosis and Paget's disease and mainly include antiresorptive therapy. New recommendations for treatment of primary hyperparathyroidism are discussed as well as therapy for calcium, phosphorus, and mineral disorders.

© 2014 Elsevier B.V. All rights reserved.

Address: Loyola University Osteoporosis and Metabolic Bone Disease Center, Loyola University Medical Center, Maywood, IL, USA.; Edward Hines Jr. VA Hospital, Hines, IL, USA.; Loyola University Osteoporosis and Metabolic Bone Disease Center, Loyola University Medical Center, Maywood, IL, USA. Electronic address: [email protected].

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