Secondary Hyperparathyroidism.

Brendan C Stack

Journal: Otolaryngologic clinics of North America 2023;57(1):99-110

PMID: 37634982

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Abstract

Secondary hyperparathyroidism (SHPT) does not initiate as a primary dysfunction of parathyroid glands resulting from an intrinsic defect or disease but is the physiologic response of parathyroids to metabolic changes elsewhere in the body occurring over time. SHPT is a manifestation of a chronic condition that classically occurs from chronic kidney disease. In fact, given the relatively recent transition of populations from outside (agrarian) to indoor (industrial, information technology, and so forth) employment and a consequent reduction in sun exposure, combined with diets of highly processed food, vitamin D and calcium deficiencies are now the leading causes of SHPT.

Address: Department of Otolaryngology-HNS Southern Illinois University/SIU Medicine, 720 North Bond Street, PO Box 19662, Springfield, IL 62794-9662, USA. Electronic address: [email protected].

DOI: 10.1016/j.otc.2023.07.010

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MeSH Terms: Humans, Parathyroid Hormone, Hyperparathyroidism, Secondary, Parathyroid Glands, Vitamin D, Vitamins