Controlling Intestinal Infections and Digestive Disorders Using Probiotics.

Rubina Roy, Gulab D Khedkar, Monica Puniya, Harmeet Singh Dhillon, Vaishali Dasriya, Manisha Sehrawat, Indira Gahatraj, Eman Shama, Rudrarup Bhattacharjee, Mrinal Samtiya, Priyakshi Nath, António Raposo, Md Faruque Ahmad, Rotimi E Aluko, Anil Kumar Puniya, Sanjeev Kumar, Tejpal Dhewa

Journal: Journal of medicinal food 2023;26(10):705-720

PMID: 37646629

Abstract

After consumption, probiotics provide health benefits to the host. Probiotics and their metabolites have therapeutic and nutritional properties that help to alleviate gastrointestinal, neurological, and cardiovascular problems. Probiotics strengthen host immunity through various mechanisms, including improved gut barrier function, receptor site blocking, competitive exclusion of pathogens, and the production of bioactive molecules. Emerging evidence suggests that intestinal bowel diseases can be fatal, but regular probiotic consumption can alleviate disease symptoms. The use and detailed description of the health benefits of probiotics to consumers in terms of reducing intestinal infection, inflammation, and digestive disorders are discussed in this review. The well-designed and controlled studies that examined the use of probiotics to reduce life-threatening activities caused by intestinal bowel diseases are also covered. This review discussed the active principles and potency of probiotics as evidenced by the known effects on host health, in addition to providing information on the mechanism of action.

Address: Department of Life Science and Bioinformatics, Assam University, Silchar, India.; Department of Clinical Nutrition, College of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia.; Adelaide Medical School, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.; Independent Researcher, Gurgaon, India.; Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, India.; Science and Standards Division, Food Safety and Standards Authority of India, New Delhi, India.; Department of Nutrition Biology, Central University of Haryana, Mahendergarh, India.; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Canada.; Paul Hebert Centre for DNA Barcoding and Biodiversity Studies, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India.; CBIOS (Research Center for Biosciences and Health Technologies), Universidade Lusófona de Humanidades e Tecnologias, Lisboa, Portugal.

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