Preparation, structures, and biological functions of rhamnan sulfate from green seaweed of the genus Monostroma: A review.

Yongzhou Chi, Yanhui Jiang, Zhaoyu Wang, Xiaobao Nie, Si Luo

Journal: International journal of biological macromolecules 2023;249():125964

PMID: 37487994

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Abstract

Rhamnan sulfate, a rhamnose-rich sulfated polysaccharide, is present in the cell walls of green seaweed belonging to the genus Monostroma. This macromolecule demonstrates promising therapeutic properties, including anti-coagulant, thrombolytic, anti-viral, anti-obesity, and anti-inflammatory activities, which hold potential applications in food and medical industries. However, rhamnan sulfate has not garnered as much attention from researchers as other seaweed polysaccharides, including alginate, carrageenan, and fucoidan. This review discusses the extraction and purification techniques of rhamnan sulfate, delves into its chemical structures and related elucidation approaches, and provides an overview of its biological functions. Future research should focus on the structure-activity relationship of rhamnan sulfate and the industrial preparation of rhamnan sulfate with a specific homogeneous structure to facilitate its practical applications.

Address: School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, Jiangsu 223003, China. Electronic address: [email protected].; Faculty of Electronic Information Engineering, Huaiyin Institute of Technology, Huai'an, Jiangsu 223003, China.; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, Jiangsu 223003, China.

DOI: 10.1016/j.ijbiomac.2023.125964

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MeSH Terms: Seaweed, Sulfates, Mannans, Chlorophyta, Polysaccharides, Antiviral Agents, Vegetables