Intraoperative ventilatory leak: Real-time guidance for management of air leak in lung cancer patients undergoing VATS lobectomy.

Gaetana Messina, Giovanni Natale, Mary Bove, Giorgia Opromolla, Vincenzo Di Filippo, Mario Martone, Antonio Noro, Beatrice Leonardi, Rosa Mirra, Francesca Capasso, Davide Gerardo Pica, Mario Grande, Francesco Panini D'alba, Giuseppe Vicario, Giovanni Liguori, Roberta Fiorito, Massimo Ciaravola, Eva Massimilla, Giovanni Messina, Alfonso Fiorelli, Giovanni Vicidomini, Fortunato Ciardiello, Morena Fasano

Journal: Thoracic cancer 2023;14(18):1782-1788

PMID: 37144333

Abstract

BACKGROUND

Persistent air leak (PAL) is a common complication after video-assisted thoracoscopic surgery (VATS) lobectomy. We aimed to evaluate whether the intraoperative quantitative measurement of air leaks using a mechanical ventilation test could predict PAL and identify those patients needing additional treatment for the prevention of PAL.

METHODS

This was an observational, retrospective, single-center study that included 82 patients who underwent VATS lobectomy with a mechanical ventilation test for VL. Only 2% of patients who underwent lobectomy surgery had persistent air leaks.

RESULTS

At the end of lobectomy performed in patients with non-small cell lung cancer, the lung was reinflated at a 25-30 mmH2O pressure and ventilatory leaks (VL) were calculated and in relation to the entity of the air leaks, we evaluated the most suitable intraoperative treatment to prevent persistent air leaks.

CONCLUSION

VL is an independent predictor of PAL after VATS lobectomy; it provides a real-time intraoperative guidance to identify those patients who can benefit from additional intraoperative preventive interventions to reduce PAL.

© 2023 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.

Address: Thoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Campania, Italy.; Anesthesiology and Intensive Care Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Campania, Italy.; Otorhinolaryngology Unit, Università degli Studi della Campania "Luigi Vanvitelli", Naples, Campania, Italy.; Nutrition Science, University of Foggia, Foggia, Italy.; Oncology, Department of Precision Medicine, Università della Campania "Luigi Vanvitelli", Naples, Campania, Italy.
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