Nutritional Management of Idiopathic Nephrotic Syndrome in Pediatric Age.

Graziana Lella, Luca Pecoraro, Elisa Benetti, Olivia Chapin Arnone, Giorgio Piacentini, Milena Brugnara, Angelo Pietrobelli

Journal: Medical sciences (Basel, Switzerland) 2023;11(3):47

PMID: 37606426

Abstract

Nephrotic syndrome (NS) is a common pediatric disease characterized by a dysfunction in the glomerular filtration barrier that leads to protein, fluid, and nutrient loss in urine. Corticosteroid therapy is the conventional treatment in children. Long-term complications of NS and prolonged exposure to steroids affect bones, growth, and the cardiovascular system. Diet can play an important role in preventing these complications, but there is a scarcity of scientific literature about nutritional recommendations for children with NS. They need individualized nutrition choices not only during the acute phase of the disease but also during remission to prevent the progression of kidney damage. The correct management of diet in these children requires a multidisciplinary approach that involves family pediatricians, pediatric nephrologists, dietitians, and parents.

Address: Pediatric Clinic, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37126 Verona, Italy.; Pediatric Nephrology, Department of Women's and Children's Health, University of Padua, 35122 Padua, Italy.; Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
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