Micronutrient deficiencies in patients with gastrointestinal cancer: To treat or not to treat.

Joanna Turkiewicz, Michael Garcia, Zhaoping Li, Vijaya Surampudi

Journal: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2023;38(4):749-760

PMID: 37280762

Abstract

Nutrition supplements are widely used among patients with cancer. The general public perceives supplements as more natural anticancer and antitoxicity agents, and often supplements are used without the knowledge of the treating physician. In the clinical setting, there are concerns that supplements may decrease effectiveness of chemotherapy and/or radiotherapy and, as a result, supplementation is avoided. There is a body of literature evaluating micronutrient deficiencies, supplementation, and cancer risk; however, little is known about the risks of treatment of micronutrient deficiencies in specific cancers. Of the types of cancers, patients with gastrointestinal cancers are at high risk of developing malnutrition and, subsequently, possible micronutrient deficiencies. This review aims to evaluate the effects of supplementation of specific micronutrients in patients with cancer of the digestive tract.

© 2023 American Society for Parenteral and Enteral Nutrition.

Address: Department of Medicine, Olive View-UCLA Medical Center, Sylmar, California, USA.; Center for Human Nutrition, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
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